Volume 8, Issue 2 (9-2019)
Plant Pathol. Sci. 2019, 8(2): 86-101 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Tabein S, Behjatnia S A A. (2019). Intracellular Interactions of Geminiviruses in Host Plants. Plant Pathol. Sci.. 8(2), 86-101. doi:10.29252/pps.8.2.86
URL: http://yujs.yu.ac.ir/pps/article-1-272-en.html
URL: http://yujs.yu.ac.ir/pps/article-1-272-en.html
Department of Plant Protection, Faculty of Agriculture, Shahid Chamran University of Ahvaz, Ahvaz, Iran , tabein.saeid@gmail.com
Abstract: (6274 Views)
Tabein S and Behjatnia SAA (2019) Intracellular interactions of geminiviruses in host plants. Plant Pathology Science 8(2):86-101. DOI:10.2982/PPS.8.2.86
Geminiviruses (Geminiviridae family) with small circular ssDNA genome are encoding just four to seven proteins on virion and complementary-sense strands of their genomes. To have a progressive infection, they are dependent mostly on host cellular machineries and interact with wide range of different host plants factors and processes. Geminiviruses alter the cell cycle in infected plants and they can support replication of viral DNA. They change host gene expression patterns, inhibit cell death pathways, alter macromolecule trafficking and interfere with protein modification to redirect or suppress host defenses and hormones signaling. Geminiviruses encode gene silencing suppressors to interfere with post-transcriptional gene silencing and alter plant DNA methylation and microRNA (miRNA) pathways, often causing developmental abnormalities. Here, the geminiviruses are discussed as one of the most destructive plant viruses and their proteins interactions with host cell factors and pathways are described.
References
1. Adams MJ, King AM and Carstens EB (2013) Ratification vote on taxonomic proposals to International Committee on Taxonomy of Viruses. Archives of Virology 158:2023-2030. [DOI:10.1007/s00705-013-1688-5]
2. Alcaide-Loridan C and Jupin I (2012) Ubiquitin and plant viruses, let's play together! Plant Physiology 160:72-82. [DOI:10.1104/pp.112.201905]
3. Anabestani A, Behjatnia SAA, Izadpanah K, Tabein S and Accotto GP (2017) Seed transmission of Beet curly top virus and Beet curly top Iran virus in a local cultivar of petunia in Iran. Viruses 9:299-311. [DOI:10.3390/v9100299]
4. Arguello-Astorga G, Lopez-Ochoa L, Kong LJ, Orozco BM, Settlage SB and Hanley-Bowdoin L (2004) A novel motif in geminivirus replication proteins interacts with the plant retinoblastoma-related protein. Journal of Virology 78:4817-4826. [DOI:10.1128/JVI.78.9.4817-4826.2004]
5. Ascencio-Ibanez JT, Sozzani R, Lee TJ, Chu TM, Wolfinger RD, Cella R and Hanley-Bowdoin L (2008) Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. Plant Physiology 148:436-454. [DOI:10.1104/pp.108.121038]
6. Bachmair A, Becker F, Masterson RV and Schell J (1990) Perturbation of the ubiquitin system causes leaf curling, vascular tissue alterations and necrotic lesions in a higher plant. EMBO Journal 9:4543-4549. [DOI:10.1002/j.1460-2075.1990.tb07906.x]
7. Bagewadi B, Chen S, Lal SK, Choudhury NR and Mukherjee SK (2004) PCNA interacts with Indian mung bean yellow mosaic virus rep and downregulates Rep activity. Journal of Virology 78:11890-11903. [DOI:10.1128/JVI.78.21.11890-11903.2004]
8. Behjatnia SAA, Dry IB and Rezaian MA (1998) Identification of the replication-associated protein binding domain within the intergenic region of tomato leaf curl geminivirus. Nucleic Acids Research 26:925-931. [DOI:10.1093/nar/26.4.925]
9. Briddon RW, Bull SE, Amin I, Mansoor S, Bedford ID, Rishi N, Siwatch SS, Zafar Y, Abdel-salam AM and Markham PG (2004) Diversity of DNA 1: A satellite molecule-like molecule associated with monopartite begomovirus-DNA β complexes. Virology 324:462-74. [DOI:10.1016/j.virol.2004.03.041]
10. Briddon RW, Pinner MS, Stanley J and Markham PG (1990) Geminivirus coat protein replacement alters insect specificity. Virology 177: 85-94. [DOI:10.1016/0042-6822(90)90462-Z]
11. Brown JK, Fauquet CM, Briddon RW, Zerbini M, Moriones E and Navas-Castillo J (2012) Geminiviridae. Pp. 351-373. In: Virus taxonomy, ninth report of the international committee on taxonomy of viruses. AMQ King MJ Adams EB. Carstens and EJLefkowitz (Eds.). London, Elsevier/Academic Press. [DOI:10.1016/B978-0-12-384684-6.00035-5]
12. Carvalho CM, Machado JP, Zerbini FM and Fontes EPB (2008a) NSP- interacting GTPase: a cytosolic protein as cofactor for nuclear shuttle proteins. Plant Signalling and Behavior 3:752-754. [DOI:10.4161/psb.3.9.6641]
13. Castillo AG, Collinet D, Deret S, Kashoggi A and Bejarano ER (2003) Dual interaction of plant PCNA with geminivirus replication accessory protein (REn) and viral replication protein (Rep). Virology 312:381-394. [DOI:10.1016/S0042-6822(03)00234-4]
14. Castillo A. G., Kong L. J., Hanley-Bowdoin L. and Bejarano E. R. 2004. Interaction between a Geminivirus Replication Protein and the Plant Sumoylation System. Journal of Virology 78:2758-2769. [DOI:10.1128/JVI.78.6.2758-2769.2004]
15. Castro PH, Tavares RM, Bejarano ER and Azevedo H (2012) SUMO, a heavyweight player in plant abiotic stress responses. Cell and Molecular Life Sciences 69:3269-3283. [DOI:10.1007/s00018-012-1094-2]
16. Chen H, Zhang Z, Teng K, Lai J, Zhang Y, Huang Y, Li Y, Liang L, Wang Y, Chu C, Guo H (2010) Up‑regulation of LSB1/GDU3 affects geminivirus infection by activating the salicylic acid pathway. Plant Journal 62:12-23. [DOI:10.1111/j.1365-313X.2009.04120.x]
17. Desvoyes B, Ramirez-Parra E, Xie Q, Chua NH and Gutierrez C (2006) Cell type-specific role of the retinoblastoma/E2F pathway during Arabidopsis leaf development. Plant Physiology 140:67-80. [DOI:10.1104/pp.105.071027]
18. Dogra SC, Eini O, Rezaian MA and Randles JW (2009) A novel shaggy-like kinase interacts with the Tomato leaf curl virus pathogenicity determinant C4 protein. Plant Molecular Biology 71:25-38. [DOI:10.1007/s11103-009-9506-x]
19. Egelkrout EM, Robertson D and Hanley-Bowdoin L (2001) Proliferating cell nuclear antigen transcription is repressed through an E2F consensus element and activated by geminivirus infection in mature leaves. Plant Cell 13:1437-1452. [DOI:10.1105/TPC.010004]
20. Eini O, Dogra S, Selth LA, Dry IB, Randles JW and Rezaian MA (2009) Interaction with a Host Ubiquitin-Conjugating Enzyme Is Required for the Pathogenicity of a Geminiviral DNA β Satellite. Molecular Plant Microbe Interaction 22:737-746. [DOI:10.1094/MPMI-22-6-0737]
21. Etessami P, Saunders K, Watts J and Stanley J (1991) Mutational analysis of complementary-sense genes of African cassava mosaic virus DNA-A. Journal of General Virology 72:1005-1012. [DOI:10.1099/0022-1317-72-5-1005]
22. Fondong VN (2013) Geminivirus protein structure and function. Molecular Plant Pathology 14:635-649. [DOI:10.1111/mpp.12032]
23. Fontes EP, Santos AA, Luz DF, Waclawovsky AJ and Chory J (2004) The geminivirus nuclear shuttle protein is a virulence factor that suppresses transmembrane receptor kinase activity. Genes and Development 18:2545-2556. [DOI:10.1101/gad.1245904]
24. Fuentes A, Carlos N, Ruiz Y, Callard D, Sánchez Y, Ochagavía ME, Seguin J, Malpica-López N, Hohn T, Lecca MR, Pérez R, Doreste V, Rehrauer H, Farinelli L, Pujol M. and Pooggin MM (2016) Field trial and molecular characterization of rnai-transgenic tomato plants that exhibit resistance to Tomato yellow leaf curl geminivirus. Molecular Plant Microbe Interaction 29:197-209. [DOI:10.1094/MPMI-08-15-0181-R]
25. Garcia-Neria MA and Rivera-Bustamante RF (2011) Characterization of geminivirus resistance in an accession of Capsicum chinense Jacq. Molecular Plant Microbe Interaction 24:172-182. [DOI:10.1094/MPMI-06-10-0126]
26. Hanley-Bowdoin L, Bejarno ER, Robertson D and Mansoor S (2013) Geminiviruses: masters at redirecting and reprogramming plant processes. Nature Reviews Microbiology 11:777-788. [DOI:10.1038/nrmicro3117]
27. Hanley-Bowdoin L, Settlage SB, Orozco BM, Nagar S and Robertson D (2000) Geminiviruses: models for plant DNA replication, transcription, and cell cycle regulation. Critical Reviews in Biochemistry and Molecular Biology 35:105-10.
28. Hao L, Wang H, Sunter G and Bisaro DM (2003) Geminivirus AL2 and L2 proteins interact with and inactivate SNF1 kinase. The Plant Cell 15:1034-1048. [DOI:10.1105/tpc.009530]
29. Kaliappan K, Choudhury NR, Suyal G and Mukherjee SK (2012) A novel role for RAD54: this host protein modulates geminiviral DNA replication. The journal of the federation of America Societies for Experimental Biology 26:1142-1160. [DOI:10.1096/fj.11-188508]
30. Kil EJ, Kim S, Lee YJ, Byuan HS, Park J, Seo H., Kim CS, Shim JK, Lee JH, Kim J K, Lee KY, Choi HS and Lee S (2016) Tomato yellow leaf curl virus (TYLCV-IL): a seed transmissible geminivirus in tomatoes. Scientific Reports 6:19013. [DOI:10.1038/srep19013]
31. Kim J, Kil EJ, Kim S Seo H, Byun HS, Park J, Chung MN, Kwak HR Kim MK, Kim CS, Yang JW, Lee KY, Choi HS and Lee S (2015) Seed transmission of Sweet potato leaf curl virus in sweet potato (Ipomoea batatas). Plant Pathology 64:1284-1291. [DOI:10.1111/ppa.12366]
32. Kong LJ and Hanley-Bowdoin L (2002) A geminivirus replication protein interacts with a protein kinase and a motor protein that display different expression patterns during plant development and infection. Plant Cell 14:1817-1832. [DOI:10.1105/tpc.003681]
33. Kong LJ, Orozco B, Roe JL, Nagar S, Ou S, Feiler HS, Durfee T, Miller AB, Gruissem W, Robertson D and Hanley-Bowdoin L (2000) A geminivirus replication protein interacts with the retinoblastoma protein through a novel domain to determine symptoms and tissue specificity of infection in plants. The EMBO Journal 19:3485-3495. [DOI:10.1093/emboj/19.13.3485]
34. Lai J, Chen H, Teng K, Zhao Q, Zhang Z, Li Y, Liang L, Xia R, Wu Y, Gou H and Xie Q (2009) RKP, a RING finger E3 ligase induced by BSCTV C4 protein, affects geminivirus infection by regulation of the plant cell cycle. The Plant Journal 57:905-917. [DOI:10.1111/j.1365-313X.2008.03737.x]
35. Lefeuvre P, Martin DP, Harkins G, Lemey P, Gray AJ, Meredith S, Lakay F, Monjane A, Lett JM, Varsani A, Heydarnejad J (2010) The spread of tomato yellow leaf curl virus from the Middle East to the world. PLoS Pathogens 6:e1001164. [DOI:10.1371/journal.ppat.1001164]
36. Legg JP and Fauquet CM (2004) Cassava mosaic geminiviruses in Africa. Plant Molecular Biology 56:585-599. [DOI:10.1007/s11103-004-1651-7]
37. Lima AT, Sobrinho RR, Gonzalez-Aguilera J, Rocha CS, Silva SJ, Xavier CA, Silva FN, Duffy S, Zerbini FM (2012) Synonymous site variation due to recombination explains higher variability in begomovirus populations infecting non-cultivated hosts. Journal of General Virology 94:418-431. [DOI:10.1099/vir.0.047241-0]
38. Liu H, Lucy AP, Davies J and Boulton MI (2001) A single amino acid change in the coat protein of Maize streak virus abolishes systemic infection, but not interaction with viral DNA or movement protein. Molecular Plant Pathology 2:223-228. [DOI:10.1046/j.1464-6722.2001.00068.x]
39. Lozano-Duran R, Rosas-Díaz T, Gusmaroli G, Luna AP, Taconnat L, Deng XW, Bejarano ER (2011b) Geminiviruses subvert ubiquitination by altering CSN-mediated derubylation of SCF E3 ligase complexes and inhibit jasmonate signaling in Arabidopsis thaliana. Plant Cell 23:1014-1032. [DOI:10.1105/tpc.110.080267]
40. Lozano-Duran R, Rosas-Diaz T, Luna AP and Bejarano ER (2011a) Identification of host genes involved in geminivirus infection using a reverse genetics approach. PLoS ONE 6:e22383. [DOI:10.1371/journal.pone.0022383]
41. Luque A, Sanz-Burgos AP, Ramirez-Parra E, Castellano MM and Gutierrez C (2002) Interaction of geminivirus Rep protein with replication factor C and its potential role during geminivirus DNA replication. Virology 302:83-94. [DOI:10.1006/viro.2002.1599]
42. Mansoor S, Zafar Y and Briddon RW (2006) Geminivirus disease complexes: the threat is spreading. Trends of Plant Science 11: 209-212. [DOI:10.1016/j.tplants.2006.03.003]
43. Marino D, Peeters N and Rivas S (2012) Ubiquitination during plant immune signaling. Plant Physiology 160:15-27. [DOI:10.1104/pp.112.199281]
44. Mehta D, Mehta D, Hirsch-Hoffmann M, Were M, Patrignani A, Zaidi SS, Were H, Gruissem W, Vanderschuren H (2018) A new full-length circular DNA sequencing method for viral-sized genomes reveals that RNAi transgenic plants provoke a shift in geminivirus populations in the field. Nucleic Acids Research 47:e9-e9. [DOI:10.1093/nar/gky914]
45. Mubin M, Briddon RW and Mansoor S (2018) The V2 protein encoded by a monopartite begomovirus is a suppressor of both post-transcriptional and transcriptional gene silencing activity. Gene 686:43-48. [DOI:10.1016/j.gene.2018.11.002]
46. Nagar S, Pedersen TJ, Carrick KM, Hanley-Bowdoin L and Robertson D (1995) A geminivirus induces expression of a host DNA synthesis protein in terminally differentiated plant cells. Plant Cell 7:705-719. [DOI:10.1105/tpc.7.6.705]
47. Navas-Castillo J, Fiallo-Olive E and Sanchez-Campos S (2011) Emerging virus diseases transmitted by whiteflies. Annual Review of Phytopathology 49:219-248. [DOI:10.1146/annurev-phyto-072910-095235]
48. Nawaz-ul-Rehman MS and Fauquet C (2009) Evolution of geminiviruses and their satellites. Federation of European Biochemical Societies 583:1825-1832. [DOI:10.1016/j.febslet.2009.05.045]
49. Piroux M, Saunders K, Page A and Stanley J (2007) Geminivirus pathogenicity protein C4 interacts with Arabidopsis thaliana shaggy-related protein kinase AtSKη, a component of the brassinosteroid signaling pathway. Virology 362:428-440. [DOI:10.1016/j.virol.2006.12.034]
50. Pooggin MM (2018) Small RNA-omics for plant virus identification, virome reconstruction and antiviral defense characterization. Frontiers in Microbiology 9:2779. [DOI:10.3389/fmicb.2018.02779]
51. Raja P, Wolf JN and Bisaro DM (2009) RNA silencing directed against geminiviruses: Post-transcriptional and epigenetic components. Biochimica et Biophysica Acta 1799:337-351. [DOI:10.1016/j.bbagrm.2010.01.004]
52. Ramesh SV, Sahu P, Prasad M, Prasad M, Praveen S, Pappu HR (2017) Geminiviruses and Plant Hosts: A Closer Examination of the Molecular Arms Race. Viruses 9:256. [DOI:10.3390/v9090256]
53. Rocha CS, Santos AA, Machado JP and Fontes EP (2008) The ribosomal protein L10/QM‑like protein is a component of the NIK-mediated antiviral signaling. Virology 380:165-169. [DOI:10.1016/j.virol.2008.08.005]
54. Saeed M, Behjatnia SAA, Mansoor S, Zafar Y, Hasnain S and Rezaian MA (2005) A single complementary sense transcript of a geminiviral DNA β satellite is determinant of pathogenicity. Molecular Plant Microbe Intraction 18:7-14. [DOI:10.1094/MPMI-18-0007]
55. Saeed M, Briddon RW, Dalakouras A, Krczal G and Wassenegger M (2015) Functional analysis of Cotton leaf curl kokhran virus/Cotton leaf curl Multan betasatellite RNA silencing suppressors. Biology 4:697-714. [DOI:10.3390/biology4040697]
56. Santos AA, Carvalho CM, Florentino LH, Ramos HJ and Fontes EP (2009) Conserved threonine residues within the A‑loop of the receptor NIK differentially regulate the kinase function required for antiviral signaling. PLoS ONE 4:e5781. [DOI:10.1371/journal.pone.0005781]
57. Scholthof KB Scholthof KB, Adkins S, Czosnek H, Palukaitis P, Jacquot E, Hohn T, Hohn B, Saunders K, Candresse T, Ahlquist P, Hemenway C (2011) Top 10 plant viruses in molecular plant pathology. Molecular Plant Pathology 12:938-954. [DOI:10.1111/j.1364-3703.2011.00752.x]
58. Settlage SB, See RGand Hanley-Bowdoin L (2005) Geminivirus C3 protein: replication enhancement and protein interactions. Journal of Virology 79:9885-9895. [DOI:10.1128/JVI.79.15.9885-9895.2005]
59. Shen Q, Liu Z, Song F, Xie Q, Hanley-Bowdoin L and Zhou X (2011) Tomato SISnRK1 protein interacts with and phosphorylates βC1, a pathogenesis protein encoded by a geminivirus β-satellite. Plant Physiology 157:1349-1406. [DOI:10.1104/pp.111.184648]
60. Shen W and Hanley-Bowdoin L (2006) Geminivirus infection up‑regulates the expression of two Arabidopsis protein kinases related to yeast SNF1- and mammalian AMPK-activating kinases. Plant Physiology 142:1642-1655. [DOI:10.1104/pp.106.088476]
61. Shen W, Reyes MI and Hanley-Bowdoin L (2009) Arabidopsis protein kinases GRIK1 and GRIK2 specifically activate SnRK1 by phosphorylating its activation loop. Plant Physiology 150:996-1005. [DOI:10.1104/pp.108.132787]
62. Shepherd DNShepherd DN, Martin DP, Van der Walt E, Dent K, Varsani A, Rybicki EP (2010) Maize streak virus: an old and complex 'emerging' pathogen. Molecular Plant Pathology 11:1-12. [DOI:10.1111/j.1364-3703.2009.00568.x]
63. Shivaprasad PV, Akbergenov R, Trinks D, Rajeswaran R, Veluthambi K, Hohn T and Pooggin MM (2005) Promoters, transcripts, and regulatory proteins of mungbean yellow mosaic geminivirus. Journal of Virology 79:8149-8163. [DOI:10.1128/JVI.79.13.8149-8163.2005]
64. Shrama P and Ikegami M (2008) RNA-silencing suppressors of geminiviruses. Journal of General Plant Pathology 74:189-202. [DOI:10.1007/s10327-008-0085-5]
65. Soitamo AJ, Jada B and Lehto K (2012) Expression of geminiviral AC2 RNA silencing suppressor changes sugar and jasmonate responsive gene expression in transgenic tobacco plants. BMC Plant Biology 12:204. [DOI:10.1186/1471-2229-12-204]
66. Stenger DC, Revington GN, Stevenson M and Bisaro DM (1991) Replicational release of geminivirus genomes from tandemly repeated copies: evidence for rolling-circle replication of a plant viral DNA. Proceeding of National Academy of Science of the United States of America 88:8029-8033. [DOI:10.1073/pnas.88.18.8029]
67. Tabein S and Behjatnia SAA (2014) Defective and satellite dnas of plant dna viruses. Plant Pathology Science 3:21-32. (In Persian with English Abstract).
68. Vanitharani R, Chellappan P, Pita JS and Fauquet CM (2004) Differential roles of AC2 and AC4 of cassava geminiviruses in mediating synergism and suppression of posttranscriptional gene silencing. Journal of Virology 78:9487-9498. [DOI:10.1128/JVI.78.17.9487-9498.2004]
69. Varsani A, Roumagnac P, Fuchs M, Navas-Castillo J, Moriones E, Idris A, Briddon RW, River-Bustamante R, Zerbini FM and Martin DP (2017) Capulavirus and Grablovirus: two new genera in the family Geminiviridae. Archives of Virology 162:1819-1831. [DOI:10.1007/s00705-017-3268-6]
70. Wang H, Buckley KJ, Ynag X, Buchmann RC and Bisaro DM (2005) Adenosine kinase inhibition and suppression of RNA silencing by geminivirus AL2 and L2 proteins. Journal of Virology 79:7410-7418. [DOI:10.1128/JVI.79.12.7410-7418.2005]
71. Yang X, Xie Y, Raja P, Li S, Wolf JN, Shen Q, Bisaro DM, Zhou X. Suppression of methylation-mediated transcriptional gene silencing by βC1-SAHH protein interaction during geminivirus-betasatellite infection. PLoS Pathogens 7:e1002329. [DOI:10.1371/journal.ppat.1002329]
72. Zeng R, Liu X, Yang C and Lai J (2018) Geminivirus C4: Interplaying with Receptor-like Kinases. Trends in Plant Science 23:1044-1046. [DOI:10.1016/j.tplants.2018.09.003]
73. Zhan B, Zhao W, Li S, Yang X and Zhou X (2018) Functional scanning of apple geminivirus proteins as symptom determinants and suppressors of posttranscriptional gene silencing. Viruses 10:488. [DOI:10.3390/v10090488]
74. Zhang T, Luan JB, Qi JF, Huang CJ, Li M, Zhou XP and Liu SS (2012) Begomovirus-whitefly mutualism is achieved through repression of plant defenses by a virus pathogenicity factor. Molecular Ecology 21:1294-1304. [DOI:10.1111/j.1365-294X.2012.05457.x]
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
