This research in order to evaluate the effect of different levels of irrigation regime on yield and yield components of soybean in Urmia region at the Urmia agricultural high school Research during 2012 using split plot based on a randomized complete block design with three replications. Drought treatments (optimum irrigation 60 mm, moderate drought stress 110 mm and severe drought stress 160 mm evaporation by evaporation pan Class A) were included in main plots and the Cultivars (Clark, Williams and Onion) were allocated in subplots. The results of variance analysis showed that the effect of drought stress on seed yield, oil and protein content was significant (P<0.01), so that the maximum and minimum oil and protein value obtained by optimum irrigation and severe drought stress conditions, respectively. However, for relative water content and leaf chlorophyll, there was no significant difference. Severe drought stress reduced the grain yield by 63 and 45% compared to the optimum irrigation and moderate stress conditions, respectively. In optimum irrigation and severe drought stress conditions, the highest seed yield, oil yield and protein yield, obtained by Onion genotype. A Clark genotype in comparison with other cultivars had the minimum seed yield, in severe drought stress conditions.